Nobody warned me about the skin. Or maybe I wasn't paying enough attention. If you know me, you know the ADHD is REAL! The weight coming off was the goal. The loose skin, the dullness, the accelerated aging — nobody puts that in the brochure for Ozempic, Wegovy, or Tirzepatide. Or they did, but again... ADHD, but I digress.
Here's what's actually happening underneath: Rapid weight loss depletes NAD+. It increases oxidative stress. It reduces the collagen synthesis your skin desperately needs to keep up with the structural changes happening underneath it. And if you're not actively supporting muscle preservation during the process, you're losing the very volume that gives skin its firmness.
When I looked at what was happening to my skin on GLP-1, I did what I always do — I went to the research.
Here's the protocol I built for myself:
The Foundation — Multi Collagen Peptides:
Type I, II, III, V, and X collagen peptides with Biotin, Vitamin C, and Hyaluronic Acid. Unflavored. Goes straight into my morning coffee. This is non-negotiable. Your body cannot rebuild structural skin proteins without the raw materials. I use Micro Ingredients Multi Collagen Peptides — 13,000+ reviews, grass fed, pasture raised, viral on TikTok for good reason. https://amzn.to/4bc2HJI
The Morning Pack — Lore Radiance AM:
Five ingredients that work alongside your collagen to support everything the collagen powder doesn't cover. Creatine for muscle preservation — because muscle volume underneath is what gives skin its structure. CoQ10 for mitochondrial energy at the cellular level. NR to restore NAD+ levels depleted by caloric restriction. Berberine for insulin sensitivity via AMPK activation. Alpha Lipoic Acid to protect existing collagen from oxidative degradation.
The Evening Pack — Lore Radiance PM:
Six ingredients timed for overnight repair. Glycine — the most abundant amino acid in collagen — as the primary building block for overnight collagen synthesis. Taurine for skin elasticity and antioxidant defense. NAC as glutathione precursor, protecting structural proteins overnight. Resveratrol for cellular repair pathway activation. Magnesium glycinate for deep restorative sleep — because sleep quality determines the depth of overnight skin repair. Zinc for collagen remodeling and barrier repair.
The Skincare — Cultivated Radiance:
The topical line I'm building specifically for GLP-1 skin. Peptide matrix. AdaptaFusion™ delivery system. Formulated for skin that is rebuilding itself from the inside out. Coming soon.
The honest truth about GLP-1 skin:
It's a long game. Collagen rebuilds slowly. NAD+ restoration takes weeks. You will not see results in 7 days. What you will see over 8-12 weeks of consistent protocol is skin that is visibly firmer, more luminous, and more resilient than it would have been without the internal support.
You already made the hard decision to go on GLP-1. You're doing the work. Your skin deserves the same intention.
This is your lore. Know it.
Affiliate Disclosure
This post contains affiliate links. If you purchase through these links, we may earn a commission at no additional cost to you. We only recommend products and services that align with our commitment to evidence-based wellness protocols. All opinions and recommendations are our own and rooted in truth.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before beginning any supplement protocol, especially if you are taking GLP-1 medications.
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